Applied ML Specialist, Biology
Build practical modelling workflows for assay prioritisation and experimental planning in a team that wants reliable prediction tools, not a research demo with a good slide deck.
About the role
Own the applied modelling layer for a biology team that wants better decisions around which assays to run, which follow-ups to prioritise, and where weak data should not be over-interpreted. The role sits between experimental scientists and software-minded colleagues, and it needs someone who can ship useful tools without pretending that the underlying data is cleaner than it is.
Role details
- Stage
- Growth-stage precision medicine group, 48 people, applied AI pod of 3
- Reporting line
- Director, Translational Data
- Rhythm
- Remote across the US with quarterly in-person working sessions
What you'll do
- Build models with a clear use case: Train and iterate on models for assay prioritisation, experimental triage, and readout interpretation where the value is operational, not academic.
- Make outputs trustworthy: Design evaluation schemes, confidence signals, and failure checks that help scientists understand when to lean on a model and when to ignore it.
- Shape usable data inputs: Work with biology and data partners to improve labels, metadata, and lineage so models are based on something sturdier than convenience exports.
- Ship tools that people actually keep using: Turn one-off analyses into lightweight workflows or interfaces that slot into existing scientific routines instead of asking the team to change everything at once.
Requirements
- Strong applied machine learning background with evidence of shipping useful models into real workflows rather than stopping at experimentation.
- Comfort working with noisy biological or healthcare-adjacent datasets where labels, metadata, and context are imperfect.
- Hands-on Python experience across modelling, evaluation, and readable implementation, using modern ML tooling where appropriate.
- Ability to explain uncertainty, edge cases, and tradeoffs to experimental stakeholders without either overselling or paralysing the work.
- Preference for specialist IC ownership over people management, with enough independence to set a high technical bar in a lean team.
Nice to have
- Experience in drug discovery, translational biology, assay modelling, or related applied scientific settings.
- Familiarity with PyTorch, gradient boosting, representation learning, or graph-based methods.
- Exposure to MLOps patterns such as experiment tracking, model registries, or scheduled retraining.
- Past work in distributed teams where clarity in written communication mattered as much as meetings.
Tools and environment
Python, PyTorch, scikit-learn, SQL, Weights & Biases, Docker, GCP, GitHub Actions
Compensation and package
- Base salary
- $150k-$185k, depending on applied scope and scientific context depth
- Equity
- Meaningful option grant plus annual cash bonus
- Travel
- Quarterly meetups and team travel covered in full
- Timing
- Fresh search tied to a broader rebuild of the internal modelling stack
Interview process
- 1.Talent screen: Conversation on compensation, remote preferences, and whether your background is closer to research ML or applied delivery.
- 2.Manager deep dive: Technical discussion on modelling choices, evaluation, and how you decide what should or should not become productionised.
- 3.Working session: Review a practical modelling brief and explain what you would build first, what you would ignore, and why.
- 4.Panel final: Cross-functional interviews with biology, product-minded stakeholders, and data partners before references and offer.
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